Search on: JNK MITOGEN-ACTIVATED PROTEIN KINASES 
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Descriptor English:   JNK Mitogen-Activated Protein Kinases 
Descriptor Spanish:   Proteínas Quinasas Activadas por JNK Mitógeno 
Descriptor Portuguese:   Proteínas Quinases JNK Ativadas por Mitógeno 
Tree Number:   D08.811.913.696.620.682.700.567.513
D08.811.913.696.620.682.700.646.750.374
D12.644.360.450.340
D12.776.476.450.340
Definition English:   A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION. 
Indexing Annotation English:   note specifics
History Note English:   2005 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   38731 
Unique Identifier:   D048031 

Occurrence in VHL:
 

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